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SERUM ACTIN INHIBITORY PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Gelsolin
Descriptor
Spanish
:
Gelsolina
Descriptor
Portuguese
:
Gelsolina
Synonyms
English
:
Gelsolin Protein
Serum Actin Inhibitory Protein
Tree Number:
D05.750.078.730.350
D12.644.360.381.437
D12.776.157.125.412.437
D12.776.220.525.350
D12.776.476.387.437
Definition
English
:
A 90-kDa protein produced by
macrophages
that severs ACTIN filaments and forms a cap on the newly exposed filament end.
Gelsolin
is activated by
CALCIUM
ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.
History Note
English
:
1994(1980)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
31448
Unique Identifier:
D018260
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS